Vaccine adjuvants : preparation methods and research protocols /

Vaccine adjuvants : preparation methods and research protocols / edited by Derek T. O'Hagan. - Totowa, N.J. : Humana Press, 2000. - 1 online resource (x, 342 pages) : illustrations - Methods in molecular medicine ; v. 42 . - Methods in molecular medicine ; v. 42. .

Source of title; title from title screen.

Includes bibliographical references and index.

An overview of adjuvant use -- Harmful and beneficial activities of immunological adjuvants -- Freund's adjuvants -- Aluminum compounds as vaccine adjuvants -- Poly(lactice-coglycolide) microparticles as vaccine adjuvants -- Poly(methyl methacrylate) nanoparticles as vaccine adjuvants -- Aqueous formulation of adjuvant-active nonionic block copolymers -- Liposomes as immunological adjuvants and vaccine carriers -- Immunopotentiating reconstituted indluezna virosomes (IRIVs) -- Cochleates for induction of mucosal and systemic immune responses -- Virus-like particles as vaccine adjuvants -- The adjuvant MF59: a 10 year perspective -- Preparation of the syntex adjuvant formulation (SAF, SAF-m, SAF-1) -- The ISCOM technology -- QS-21 adjuvant -- MPL Immunostimulant: adjuvant formulations -- Cytokines as vaccine adjuvants: the use of interleukin-2 -- DNA as an adjuvant -- Transcutaneous immunizaation -- Mutant heat-lbile enterotoxins as adjuvants for CTL induction.

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Annotation Derek T. O'Hagan and a team of expert vaccinologists and pharmacologists thoroughly describe the preparation, characterization, and evaluation of a wide range of alternative vaccine adjuvants for use in preclinical studies. Each chapter carefully reviews a single adjuvant, and suggests why a specific adjuvant might be preferred for a given antigen, depending on what type of immune response is desired. Alternate adjuvant choices are also presented so that researchers can choose those most efficacious for their specific purpose. Comprehensive and highly practical, Vaccine Adjuvants: Preparation Methods and Research Protocols provides an effective guide to making and using vaccine adjuvants. By closely following directions from the book, today's researchers will be able optimally to induce specific immune responses against different types of antigens and to selectively manipulate the immune response in a favorable way.

Electronic reproduction.
[Place of publication not identified] :
HathiTrust Digital Library,

Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.


9781592590834 1592590837 128082073X 9781280820731 9786610820733 6610820732

10.1385/1592590837. doi

Immunological adjuvants.
Adjuvants, Immunologic.
Immunologic Factors.
Biological Products.
Complex Mixtures.
Physiological Effects of Drugs
Chemicals and Drugs
Pharmacologic Actions
Chemical Actions and Uses
Immunological adjuvants.
Wetenschappelijke technieken.

Electronic books.

QR187.3 / .V33 2000


QW 805 / V1154 2000

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