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07946cam a2201129Ia 4500 |
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ocn658061262 |
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OCoLC |
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OCoLC |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20200626145824.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
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m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr ||||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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| fixed length control field |
100825s2010 njua ob 001 0 eng |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
SCB |
| Language of cataloging |
eng |
| Description conventions |
pn |
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SCB |
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CUV |
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GW5XE |
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CUS |
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OCLCQ |
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UAB |
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MERER |
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LIP |
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OTZ |
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OCLCQ |
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WURST |
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OCLCA |
| 015 ## - NATIONAL BIBLIOGRAPHY NUMBER |
|---|
| National bibliography number |
GBB067998 |
| Source |
bnb |
| 016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER |
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| Record control number |
015567082 |
| Source |
Uk |
| 019 ## - |
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| -- |
664246525 |
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771208752 |
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853260174 |
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859634184 |
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864812541 |
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889153198 |
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964912886 |
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967616570 |
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990408888 |
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1005786903 |
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1027557618 |
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1058240859 |
| -- |
1081229056 |
| -- |
1087028481 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9781607617563 |
| Qualifying information |
(e-ISBN) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
1607617560 |
| Qualifying information |
(e-ISBN) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| Canceled/invalid ISBN |
9781607617556 |
| Qualifying information |
(hbk.) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| Canceled/invalid ISBN |
1607617552 |
| Qualifying information |
(hbk.) |
| 024 7# - OTHER STANDARD IDENTIFIER |
|---|
| Standard number or code |
10.1007/978-1-60761-756-3 |
| Source of number or code |
doi |
| 029 1# - (OCLC) |
|---|
| OCLC library identifier |
AU@ |
| System control number |
000061124762 |
| 029 1# - (OCLC) |
|---|
| OCLC library identifier |
NZ1 |
| System control number |
15212419 |
| 035 ## - SYSTEM CONTROL NUMBER |
|---|
| System control number |
(OCoLC)658061262 |
| Canceled/invalid control number |
(OCoLC)664246525 |
| -- |
(OCoLC)771208752 |
| -- |
(OCoLC)853260174 |
| -- |
(OCoLC)859634184 |
| -- |
(OCoLC)864812541 |
| -- |
(OCoLC)889153198 |
| -- |
(OCoLC)964912886 |
| -- |
(OCoLC)967616570 |
| -- |
(OCoLC)990408888 |
| -- |
(OCoLC)1005786903 |
| -- |
(OCoLC)1027557618 |
| -- |
(OCoLC)1058240859 |
| -- |
(OCoLC)1081229056 |
| -- |
(OCoLC)1087028481 |
| 037 ## - SOURCE OF ACQUISITION |
|---|
| Stock number |
978-1-60761-755-6 |
| Source of stock number/acquisition |
Springer |
| Note |
http://www.springerlink.com |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
|---|
| Classification number |
QP551 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER |
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| Classification number |
QU 55.9 |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
PSF |
| Source |
bicssc |
| 072 #7 - SUBJECT CATEGORY CODE |
|---|
| Subject category code |
SCI049000 |
| Source |
bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
611.01815 |
| Edition number |
22 |
| 049 ## - LOCAL HOLDINGS (OCLC) |
|---|
| Holding library |
MAIN |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
Protein misfolding and cellular stress in disease and aging : |
| Remainder of title |
concepts and protocols / |
| Statement of responsibility, etc. |
edited by Peter Bross and Niels Gregersen. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication, distribution, etc. |
Totowa, N.J. : |
| Name of publisher, distributor, etc. |
Humana ; |
| Place of publication, distribution, etc. |
London : |
| Name of publisher, distributor, etc. |
Springer [distributor], |
| Date of publication, distribution, etc. |
2010. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
1 online resource (xi, 330 pages) : |
| Other physical details |
illustrations |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Content type code |
txt |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
computer |
| Media type code |
c |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
online resource |
| Carrier type code |
cr |
| Source |
rdacarrier |
| 347 ## - DIGITAL FILE CHARACTERISTICS |
|---|
| File type |
text file |
| Source |
rda |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Springer protocols |
| 490 1# - SERIES STATEMENT |
|---|
| Series statement |
Methods in molecular biology, |
| International Standard Serial Number |
1064-3745 ; |
| Volume/sequential designation |
648 |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc |
Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Protein misfolding and cellular stress : an overview -- Protein aggregation diseases: toxicity of soluble prefibrillar aggregates and their clinical significance -- Consequences of stress in the secretary pathway : the ER stress response and its role in the metabolic syndrome -- What role does mitochondrial stress play in neurodegenerative diseases? -- Autophagy in disease -- Mitophagy and mitoptosis in disease processes -- Cellular stress and protein misfolding during aging -- Measuring consequences of protein misfolding and cellular stress using OMICS techniques -- Production of cells with targeted integration of gene variants of human ABC transporter for stable and regulated expression using the Flp recombinase system -- Stress response profiles in human fibroblasts exposed to heat shock or oxidative stress -- Examining ubiquitinated protein aggregates in tissue sections -- Determination of proteasomal activities -- Measurement of autophagy in cells and tissues -- Transcription factor sequestration by polyglutamine proteins -- Biological membranes as protein aggregation matrices and targets of amyloid toxicity -- Measurement of mitochondrial ROS production -- In vivo detection of oxidized proteins : a practical approach to tissue-derived mitochondria -- Measurement of oxidized/reduced glutathione ratio -- Determination of altered mitochondria ultrastructure by electron microscopy -- Assessing bad sub-cellular localization under conditions associated with prevention or promotion of mitochondrial permeability transition-dependent toxicity -- A cellular viability assay to monitor drug toxicity -- Rescue of misfolded proteins and stabilization by small molecules. |
| 588 0# - SOURCE OF DESCRIPTION NOTE |
|---|
| Source of description note |
Print version record. |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
How and why certain proteins misfold and how this misfolding is linked to many disease processes has become a well-documented topic of study. Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols moves beyond the basics to emphasize the molecular effects of protein misfolding at a cellular level, to delineate the impacts and cellular reactions that play a role in pathogenetic mechanisms, and to pinpoint possible manipulations and treatment strategies that can counteract, modify, or delay the consequences of misfolding. The volume begins with several concepts and approaches developed in the recent past including a connection to the research field of aging, where protein misfolding diseases have been equated to premature aging processes, and the book's coverage continues with detailed descriptions of protocols for relevant experimental approaches. Written in the highly successful Methods in Molecular Biology series format, protocols chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Protein Misfolding and Cellular Stress in Disease and Aging: Concepts and Protocols aims to aid researchers in the field, as well as medical professionals and molecular biologists, in shaping and performing research related to this intriguing and vital subject. |
| 546 ## - LANGUAGE NOTE |
|---|
| Language note |
English. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Protein folding. |
| 9 (RLIN) |
18760 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Proteins |
| General subdivision |
Pathophysiology. |
| 9 (RLIN) |
86325 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pathology, Cellular. |
| 9 (RLIN) |
86326 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biophysical Phenomena. |
| 9 (RLIN) |
85238 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
| 9 (RLIN) |
2865 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Anatomy. |
| 9 (RLIN) |
43781 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Publication Formats |
| 9 (RLIN) |
15957 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biological Science Disciplines. |
| 9 (RLIN) |
12496 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Biochemical Phenomena. |
| 9 (RLIN) |
5597 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Growth and Development. |
| 9 (RLIN) |
71125 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Amino Acids, Peptides, and Proteins |
| 9 (RLIN) |
79921 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Physical Phenomena. |
| 9 (RLIN) |
78460 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Health Occupations. |
| 9 (RLIN) |
50394 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Publication Characteristics |
| 9 (RLIN) |
15959 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Physiological Phenomena. |
| 9 (RLIN) |
6339 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Chemicals and Drugs |
| 9 (RLIN) |
13222 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Chemical Phenomena. |
| 9 (RLIN) |
86327 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Natural Science Disciplines. |
| 9 (RLIN) |
12499 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Protein Folding. |
| 9 (RLIN) |
18760 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Laboratory Manuals |
| 9 (RLIN) |
81487 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Proteins. |
| 9 (RLIN) |
79920 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Physiology. |
| 9 (RLIN) |
44570 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Aging. |
| 9 (RLIN) |
80158 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pathology. |
| 9 (RLIN) |
80598 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Cells. |
| 9 (RLIN) |
2745 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Disciplines and Occupations |
| 9 (RLIN) |
12501 |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Phenomena and Processes |
| 9 (RLIN) |
12502 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pathology, Cellular. |
| Source of heading or term |
fast |
| Authority record control number |
(OCoLC)fst01054974 |
| 9 (RLIN) |
86326 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Protein folding. |
| Source of heading or term |
fast |
| Authority record control number |
(OCoLC)fst01079687 |
| 9 (RLIN) |
18760 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Human Anatomy & Physiology. |
| Source of heading or term |
hilcc |
| 9 (RLIN) |
70648 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Medicine. |
| Source of heading or term |
hilcc |
| 9 (RLIN) |
2865 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Health & Biological Sciences. |
| Source of heading or term |
hilcc |
| 9 (RLIN) |
24083 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Animal Biochemistry. |
| Source of heading or term |
hilcc |
| 9 (RLIN) |
70647 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name as entry element |
Pathology. |
| Source of heading or term |
hilcc |
| 9 (RLIN) |
80598 |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
celbiologie |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
cellular biology |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
levenswetenschappen |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
life sciences |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
eiwitexpressieanalyse |
| 653 00 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
proteomics |
| 653 10 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Medicine (General) |
| 653 10 - INDEX TERM--UNCONTROLLED |
|---|
| Uncontrolled term |
Geneeskunde (algemeen) |
| 655 #4 - INDEX TERM--GENRE/FORM |
|---|
| Genre/form data or focus term |
Electronic books. |
| 9 (RLIN) |
396 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Bross, Peter. |
| 9 (RLIN) |
83359 |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Gregersen, Niels. |
| 9 (RLIN) |
83360 |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
|---|
| Relationship information |
Print version: |
| Title |
Protein misfolding and cellular stress in disease and aging. |
| Place, publisher, and date of publication |
Totowa, N.J. : Humana ; London : Springer [distributor], 2010 |
| International Standard Book Number |
9781607617556 |
| Record control number |
(DLC) 2010931837 |
| -- |
(OCoLC)636917493 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Springer protocols (Series) |
| 9 (RLIN) |
80328 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
|---|
| Uniform title |
Methods in molecular biology (Clifton, N.J.) ; |
| Volume number/sequential designation |
v. 648. |
| 9 (RLIN) |
86328 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
|---|
| Uniform Resource Identifier |
<a href="https://link-springer-com.libraryproxy.ist.ac.at/10.1007/978-1-60761-756-3">https://link-springer-com.libraryproxy.ist.ac.at/10.1007/978-1-60761-756-3</a> |
| 938 ## - |
|---|
| -- |
YBP Library Services |
| -- |
YANK |
| -- |
3531815 |
| 994 ## - |
|---|
| -- |
92 |
| -- |
ATIST |