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Information processing in cells and tissues : 9th International Conference, IPCAT 2012, Cambridge, UK, March 31-April 2, 2012. Proceedings / Michael A. Lones [and others] (eds.).

By: (9th : International Workshop on Information Processing in Cells and Tissues (9th : 2012 : Cambridge, England)Contributor(s): Lones, Michael AMaterial type: TextTextSeries: Serienbezeichnung | Lecture notes in computer science ; 7223. | LNCS sublibrary. SL 1, Theoretical computer science and general issues.Publication details: Berlin ; New York : Springer, ©2012. Description: 1 online resource (xii, 278 pages) : color illustrationsContent type: text Media type: computer Carrier type: online resourceISBN: 9783642287923; 3642287921; 3642287913; 9783642287916Other title: IPCAT 2012Subject(s): Cellular signal transduction -- Congresses | Cell interaction -- Congresses | Systems biology -- Congresses | Cell Communication | Gene Regulatory Networks | Models, Biological | Signal Transduction | Informatique | Cell interaction | Cellular signal transduction | Systems biology | Computer science | Bioinformatics | Computational Biology/Bioinformatics | Math Applications in Computer Science | Pattern RecognitionGenre/Form: Congress. | Electronic books. | Conference papers and proceedings. Additional physical formats: Print version:: Information processing in cells and tissues.DDC classification: 571.7/4 LOC classification: QP517.C45 | I58 2012NLM classification: 2012 D-768 | QU 375Online resources: Click here to access online
Contents:
Using Artificial Epigenetic Regulatory Networks to Control Complex Tasks within Chaotic Systems / Alexander P. Turner, Michael A. Lones, Luis A. Fuente, Susan Stepney and Leo S. Caves, et al. -- A Gene Regulatory Network Simulation of Heterosis / Peter Martin Ferdinand Emmrich, Hannah Elizabeth Roberts and Vera Pancaldi -- Comparing Discrete and Piecewise Affine Differential Equation Models of Gene Regulatory Networks / Shahrad Jamshidi, Heike Siebert and Alexander Bockmayr -- Automatic Inference of Regulatory and Dynamical Properties from Incomplete Gene Interaction and Expression Data / Fabien Corblin, Eric Fanchon, Laurent Trilling, Claudine Chaouiya and Denis Thieffry -- CRISPR Transcript Processing: An Unusual Mechanism for Rapid Production of Desired Molecules / Marko Djordjevic, Konstantin Severinov and Magdalena Djordjevic -- A Comprehensive Computational Model to Simulate Transcription Factor Binding in Prokaryotes / Nicolae Radu Zabet and Boris Adryan -- Evolved Artificial Signalling Networks for the Control of a Conservative Complex Dynamical System / Luis A. Fuente, Michael A. Lones, Alexander P. Turner, Susan Stepney and Leo S. Caves, et al. -- The Effect of Membrane Receptor Clustering on Spatio-temporal Cell Signalling Dynamics / Bertrand R. Caré and Hédi A. Soula -- Systems Biology Analysis of Kinase Inhibitor Protein Target Profiles in Leukemia Treatments / Jacques Colinge, Uwe Rix, Keiryn L. Bennett and Giulio Superti-Furga -- Multispecific Interactions in Enzymatic Signalling Cascades / Daniel D. Seaton and J. Krishnan -- Role of Physico-chemical Properties of Amino Acids in Protein's Structural Organization: A Network Perspective / Dhriti Sengupta and Sudip Kundu -- Tailored Strategies for the Analysis of Metabolomic Data / Kristen Feher, Kathrin Jürchott and Joachim Selbig.
Evolving Locomotion for a Simulated 12-DOF Quadruped Robot / Gordon Klaus, Kyrre Glette and Mats Høvin -- Predictive Modelling of Stem Cell Differentiation and Apoptosis in C. elegans / Antje Beyer, Ralf Eberhard, Nir Piterman, Michael O. Hengartner and Alex Hajnal, et al. -- Criticality of Spatiotemporal Dynamics in Contact Mediated Pattern Formation / Nicholas S. Flann, Hamid Mohamadlou and Gregory J. Podgorski -- The Vasopressin System -- Asynchronous Burst Firing as a Signal Encoding Mechanism / Duncan J. MacGregor, Tom F. Clayton and Gareth Leng -- The Effective Calcium/Calmodulin Concentration Determines the Sensitivity of CaMKII to the Frequency of Calcium Oscillations / Thiago M. Pinto, Maria J. Schilstra and Volker Steuber -- The Effect of Different Types of Synaptic Plasticity on the Performance of Associative Memory Networks with Excitatory and Inhibitory Sub-populations / Alex Metaxas, Reinoud Maex, Volker Steuber, Rod Adams and Neil Davey -- Simulating Neurons in Reaction-Diffusion Chemistry / James Stovold and Simon O'Keefe -- Extending an Established Simulation: Exploration of the Possible Effects Using a Case Study in Experimental Autoimmune Encephalomyelitis / Richard B. Greaves, Mark Read, Jon Timmis, Paul S. Andrews and Vipin Kumar -- Human Uterine Excitation Patterns Leading to Labour: Synchronization or Propagation? / Eleftheria Pervolaraki and Arun V. Holden -- Evolving Computational Dynamical Systems to Recognise Abnormal Human Motor Function / Michael A. Lones, Stephen L. Smith, Andy M. Tyrrell, Jane E. Alty and D.R. Stuart Jamieson.
Heat-Maps and Visualization for Heterogeneous Biomedical Data Based on Information Distance Geometry / Esther Loeliger, Chrystopher L. Nehaniv and Alastair J. Munro -- Bio-inspired Information Processing Applied to Engineering Systems / Cristina Costa Santini -- Understanding the Regulation of Predatory and Anti-prey Behaviours for an Artificial Organism / Maizura Mokhtar -- Closing the Gap between Life and Physics / Ron Cottam, Willy Ranson and Roger Vounckx -- Algebraic Analysis of the Computation in the Belousov-Zhabotinksy Reaction / Paolo Dini, Chrystopher L. Nehaniv, Attila Egri-Nagy and Maria J. Schilstra -- Improving Transcription Factor Binding Site Predictions by Using Randomised Negative Examples / Faisal Rezwan, Yi Sun, Neil Davey, Rod Adams and Alistair G. Rust, et al. -- Finding the Minimal Gene Regulatory Function in the Presence of Undefined Transitional States Using a Genetic Algorithm / Rocio Chavez-Alvarez, Arturo Chavoya and Cuauhtemoc Lopez-Martin -- Extracting Tailored Protein Complexes from Protein-Protein Interaction Networks / Hiroshi Okamoto -- A Parallel Algorithm for Multiple Biological Sequence Alignment / Irma R. Andalon-Garcia, Arturo Chavoya and M.E. Meda-Campaña.
Summary: This book constitutes the refereed proceedings of the 9th International Conference on Information in Cells and Tissues, IPCAT 2012, held in Cambridge, UK, in March/April 2012. The 13 revised full papers presented together with 26 extended abstracts were carefully reviewed and selected from numerous submissions. The papers cover a wide range of topics in disciplines related to genetic and epigenetic networks, transcriptomics and gene regulation, signalling pathways and responses, protein structure and metabolic networks, patterning and rhythm generation, neural modelling and neural networks, biomedical modelling and signal processing, information processing and representation, and algorithmic approaches in computational biology.
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Includes bibliographical references and author index.

Using Artificial Epigenetic Regulatory Networks to Control Complex Tasks within Chaotic Systems / Alexander P. Turner, Michael A. Lones, Luis A. Fuente, Susan Stepney and Leo S. Caves, et al. -- A Gene Regulatory Network Simulation of Heterosis / Peter Martin Ferdinand Emmrich, Hannah Elizabeth Roberts and Vera Pancaldi -- Comparing Discrete and Piecewise Affine Differential Equation Models of Gene Regulatory Networks / Shahrad Jamshidi, Heike Siebert and Alexander Bockmayr -- Automatic Inference of Regulatory and Dynamical Properties from Incomplete Gene Interaction and Expression Data / Fabien Corblin, Eric Fanchon, Laurent Trilling, Claudine Chaouiya and Denis Thieffry -- CRISPR Transcript Processing: An Unusual Mechanism for Rapid Production of Desired Molecules / Marko Djordjevic, Konstantin Severinov and Magdalena Djordjevic -- A Comprehensive Computational Model to Simulate Transcription Factor Binding in Prokaryotes / Nicolae Radu Zabet and Boris Adryan -- Evolved Artificial Signalling Networks for the Control of a Conservative Complex Dynamical System / Luis A. Fuente, Michael A. Lones, Alexander P. Turner, Susan Stepney and Leo S. Caves, et al. -- The Effect of Membrane Receptor Clustering on Spatio-temporal Cell Signalling Dynamics / Bertrand R. Caré and Hédi A. Soula -- Systems Biology Analysis of Kinase Inhibitor Protein Target Profiles in Leukemia Treatments / Jacques Colinge, Uwe Rix, Keiryn L. Bennett and Giulio Superti-Furga -- Multispecific Interactions in Enzymatic Signalling Cascades / Daniel D. Seaton and J. Krishnan -- Role of Physico-chemical Properties of Amino Acids in Protein's Structural Organization: A Network Perspective / Dhriti Sengupta and Sudip Kundu -- Tailored Strategies for the Analysis of Metabolomic Data / Kristen Feher, Kathrin Jürchott and Joachim Selbig.

Evolving Locomotion for a Simulated 12-DOF Quadruped Robot / Gordon Klaus, Kyrre Glette and Mats Høvin -- Predictive Modelling of Stem Cell Differentiation and Apoptosis in C. elegans / Antje Beyer, Ralf Eberhard, Nir Piterman, Michael O. Hengartner and Alex Hajnal, et al. -- Criticality of Spatiotemporal Dynamics in Contact Mediated Pattern Formation / Nicholas S. Flann, Hamid Mohamadlou and Gregory J. Podgorski -- The Vasopressin System -- Asynchronous Burst Firing as a Signal Encoding Mechanism / Duncan J. MacGregor, Tom F. Clayton and Gareth Leng -- The Effective Calcium/Calmodulin Concentration Determines the Sensitivity of CaMKII to the Frequency of Calcium Oscillations / Thiago M. Pinto, Maria J. Schilstra and Volker Steuber -- The Effect of Different Types of Synaptic Plasticity on the Performance of Associative Memory Networks with Excitatory and Inhibitory Sub-populations / Alex Metaxas, Reinoud Maex, Volker Steuber, Rod Adams and Neil Davey -- Simulating Neurons in Reaction-Diffusion Chemistry / James Stovold and Simon O'Keefe -- Extending an Established Simulation: Exploration of the Possible Effects Using a Case Study in Experimental Autoimmune Encephalomyelitis / Richard B. Greaves, Mark Read, Jon Timmis, Paul S. Andrews and Vipin Kumar -- Human Uterine Excitation Patterns Leading to Labour: Synchronization or Propagation? / Eleftheria Pervolaraki and Arun V. Holden -- Evolving Computational Dynamical Systems to Recognise Abnormal Human Motor Function / Michael A. Lones, Stephen L. Smith, Andy M. Tyrrell, Jane E. Alty and D.R. Stuart Jamieson.

Heat-Maps and Visualization for Heterogeneous Biomedical Data Based on Information Distance Geometry / Esther Loeliger, Chrystopher L. Nehaniv and Alastair J. Munro -- Bio-inspired Information Processing Applied to Engineering Systems / Cristina Costa Santini -- Understanding the Regulation of Predatory and Anti-prey Behaviours for an Artificial Organism / Maizura Mokhtar -- Closing the Gap between Life and Physics / Ron Cottam, Willy Ranson and Roger Vounckx -- Algebraic Analysis of the Computation in the Belousov-Zhabotinksy Reaction / Paolo Dini, Chrystopher L. Nehaniv, Attila Egri-Nagy and Maria J. Schilstra -- Improving Transcription Factor Binding Site Predictions by Using Randomised Negative Examples / Faisal Rezwan, Yi Sun, Neil Davey, Rod Adams and Alistair G. Rust, et al. -- Finding the Minimal Gene Regulatory Function in the Presence of Undefined Transitional States Using a Genetic Algorithm / Rocio Chavez-Alvarez, Arturo Chavoya and Cuauhtemoc Lopez-Martin -- Extracting Tailored Protein Complexes from Protein-Protein Interaction Networks / Hiroshi Okamoto -- A Parallel Algorithm for Multiple Biological Sequence Alignment / Irma R. Andalon-Garcia, Arturo Chavoya and M.E. Meda-Campaña.

This book constitutes the refereed proceedings of the 9th International Conference on Information in Cells and Tissues, IPCAT 2012, held in Cambridge, UK, in March/April 2012. The 13 revised full papers presented together with 26 extended abstracts were carefully reviewed and selected from numerous submissions. The papers cover a wide range of topics in disciplines related to genetic and epigenetic networks, transcriptomics and gene regulation, signalling pathways and responses, protein structure and metabolic networks, patterning and rhythm generation, neural modelling and neural networks, biomedical modelling and signal processing, information processing and representation, and algorithmic approaches in computational biology.

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