Mathematical modeling of calcium dynamics and signal transduction / James Sneyd (ed.) ; with contributions by R. Bertram [and others].Material type: TextSeries: Tutorials in mathematical biosciences ; 2. | Lecture notes in mathematics (Springer-Verlag) ; 1867. | Lecture notes in mathematics (Springer-Verlag). Mathematical biosciences subseries.Publication details: Berlin ; New York : Springer, ©2005. Description: 1 online resource (xii, 202 pages) : illustrations (some color)Content type: text Media type: computer Carrier type: online resourceISBN: 3540254390; 9783540254393; 9783540314387; 3540314385; 9786611402402; 6611402403Subject(s): Calcium -- Physiological transport -- Mathematical models | Calcium -- Metabolism -- Mathematical models | Cellular signal transduction -- Mathematical models | Calcium -- Physiological effect -- Mathematical models | Muscle Contraction | Calcium Signaling | Models, Theoretical | Cell Physiological Phenomena | Physiology | Biological Science Disciplines | Investigative Techniques | Second Messenger Systems | Phenomena and Processes | Ion Transport | Musculoskeletal Physiological Phenomena | Biological Transport | Signal Transduction | Analytical, Diagnostic and Therapeutic Techniques and Equipment | Natural Science Disciplines | Biochemical Phenomena | Disciplines and Occupations | Metabolism | Musculoskeletal and Neural Physiological Phenomena | Chemical Phenomena | Mathematics | Mathematical Biology in General | Mathematical Modeling and Industrial Mathematics | Cell Biology | Mathematical Theory | Biology -- General | Animal Biochemistry | Mathematics | Biology | Human Anatomy & Physiology | Health & Biological Sciences | Physical Sciences & Mathematics | Transduction du signal cellulaire | Calcium -- Effets physiologiques | Calcium -- Physiological effect | Cellular signal transduction | Cellular signal transduction -- Mathematical modelsGenre/Form: Electronic books. Additional physical formats: Print version:: Mathematical modeling of calcium dynamics and signal transduction.DDC classification: 572/.516 015118 LOC classification: QP535.C2 | T87 2005QA3 | .L28 no. 1867NLM classification: 2005 J-991 | QU 55Other classification: Q42 Online resources: Click here to access online
|Item type||Current library||Collection||Call number||Status||Date due||Barcode||Item holds|
"These lectures are based on material which was presented in tutorials or developed by visitors and postdoctoral fellows of the Mathematical Bioscience Institute (MBI), at The Ohio State University"--Preface.
Includes bibliographical references.
Basic concepts of Ca² signaling in cells and tissues / M.J. Sanderson -- Modeling IP₃-dependent calcium dynamics in non-excitable cells / J. Sneyd -- Integrated calcium management in cardiac myocytes / T.R. Shannon -- Mechanisms and models of cardiac excitation-contraction coupling / R.L. Winslow, R. Hinch, J.L. Greenstein -- Mathematical analysis of the generation of force and motion in contracting muscle / E. Pate -- Signal transduction in vertebrate olfactory receptor cells / J. Reisert -- Mathematical models of synaptic transmission and short-term plasticity / R. Bertram.
This book presents a series of models in the general area of cell physiology and signal transduction, with particular attention being paid to intracellular calcium dynamics, and the role played by calcium in a variety of cell types. Calcium plays a crucial role in cell physiology, and the study of its dynamics lends insight into many different cellular processes. In particular, calcium plays a central role in muscular contraction, olfactory transduction and synaptic communication, three of the topics to be addressed in detail in this book. In addition to the models, this book also presents much of the underlying physiology, so that readers may learn both the mathematics and the physiology at the same time, and see how the models are applied to specific biological questions. It is thus neither a mathematics book nor a physiology book, but has features from both sides of the fence. It is intended primarily as a graduate text or a research reference. However, some parts of the book, particularly the introductory chapters on calcium dynamics will be well within the reach of some undergraduates. It will serve as a concise and up-to-date introduction to all those who wish to learn about the state of calcium dynamics modeling, and how such models are applied to physiological questions.