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Inflammation and cancer : methods and protocols. Volume 1, Experimental models and practical approaches / edited by Serguei V. Kozlov.

Contributor(s): Kozlov, Serguei VMaterial type: TextTextSeries: Methods in molecular biology (Clifton, N.J.) ; 511. | Springer protocols (Series)Publication details: New York : Humana Press, ©2009. Description: 1 online resource (1 volume) : illustrationsContent type: text Media type: computer Carrier type: online resourceISBN: 9781597454476; 1597454478Other title: Experimental models and practical approachesSubject(s): Cancer -- Etiology | Inflammation | Neoplasms | Laboratory Manuals | Inflammation | Pathologic Processes | Publication Formats | Disease | Pathological Conditions, Signs and Symptoms | Publication Characteristics | Inflammation | Neoplasms | Cancer -- Etiology | Cancer -- Etiology | Inflammation | neoplasms | geneeskunde | medicine | biomedische wetenschappen | biomedicine | oncologie | oncology | Medicine (General) | Geneeskunde (algemeen)Genre/Form: Laboratory Manual. | Electronic books. Additional physical formats: Print version:: Inflammation and cancer.DDC classification: 616.99/4071 LOC classification: RC268.48 | .I57 2009NLM classification: W1 | QZ 25Other classification: R730. 2 Online resources: Click here to access online
Contents:
Collection and preparation of rodent tissue samples for histopathological and molecular studies in carcinogenesis / Yelena Golubeva and Keith Rogers. Biomarkers of cell proliferation in carcinomas : detection of angiogenesis and infiltrated leukocytes / Coen I.M. Baeten. Assessment of local proteolytic milieu as a factor in tumor invasiveness and metastasis formation : in vitro collagen degradation and invasion assays / Brenda L. Petrella -- Cytokine multiplex analysis / Howard A. Young. Approaches to determine expression of inflammatory cytokines / Derk Amsen, Karin E. de Visser, and Terrence Town. Selective immortalization of tumor-specific T cells to establish long-term T-cell lines maintaining primary cell characteristics / Eugene V. Barsov. YKL-40 : a novel marker shared by chronic inflammation and oncogenic transformation / Anne Roslind and Julia S. Johansen. Angiogenesis links chronic inflammation with cancer / Hanako Kobayashi and P. Charles Lin. Inflammatory bowel disease : a model of chronic inflammation-induced cancer / Guang-Yu Yang, Sofia Taboada, and Jie Liao. Gastric carcinogenesis and Helicobacter pylori infection / Christine Varon [and others]. Helicobacter-based mouse models of digestive system carcinogenesis / Arlin B. Rogers and JeanMarie Houghton. Screening for molecular markers of cervical papillomavirus infection: overview of methods and their clinical implications / Donna Dehn [and others] Screening for Epstein-Barr virus in Hodgkin's lymphoma / Gulfaraz Khan. A hepatitis C virus xenograft mouse efficacy model / Qing Zhu and Amy J. Weiner. Gene expression profiling in cervical cancer: identification of novel markers for disease diagnosis and therapy / Cara M. Martin [and others] Detection and genotyping analysis of human papillomavirus isolates from liquid- based cervical cytology specimens / Patricia Avissar and Douglas P. Malinowski.
Summary: According to the most recent clinical oncology data, one out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. In Inflammation and Cancer: Methods and Protocols, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology, selectively focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. Volume 1, Experimental Models and Practical Approaches provides an overview of a spectrum of techniques developed to analyze the outcomes of inflammation-mediated carcinogenesis on the tissue, cellular, and molecular levels while highlighting several diagnostic aspects, such as biomarker discovery and molecular signatures evaluation. Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step laboratory protocols, and a notes section, which examines tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Inflammation and Cancer: Methods and Protocols promises to serve as a vital guide and resource for investigators and clinicians working toward the goal of combatting the estimated 2, 200 inflammation-related oncogenesis fatalities occurring every day.
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Includes bibliographical references and index.

Collection and preparation of rodent tissue samples for histopathological and molecular studies in carcinogenesis / Yelena Golubeva and Keith Rogers. Biomarkers of cell proliferation in carcinomas : detection of angiogenesis and infiltrated leukocytes / Coen I.M. Baeten. Assessment of local proteolytic milieu as a factor in tumor invasiveness and metastasis formation : in vitro collagen degradation and invasion assays / Brenda L. Petrella -- Cytokine multiplex analysis / Howard A. Young. Approaches to determine expression of inflammatory cytokines / Derk Amsen, Karin E. de Visser, and Terrence Town. Selective immortalization of tumor-specific T cells to establish long-term T-cell lines maintaining primary cell characteristics / Eugene V. Barsov. YKL-40 : a novel marker shared by chronic inflammation and oncogenic transformation / Anne Roslind and Julia S. Johansen. Angiogenesis links chronic inflammation with cancer / Hanako Kobayashi and P. Charles Lin. Inflammatory bowel disease : a model of chronic inflammation-induced cancer / Guang-Yu Yang, Sofia Taboada, and Jie Liao. Gastric carcinogenesis and Helicobacter pylori infection / Christine Varon [and others]. Helicobacter-based mouse models of digestive system carcinogenesis / Arlin B. Rogers and JeanMarie Houghton. Screening for molecular markers of cervical papillomavirus infection: overview of methods and their clinical implications / Donna Dehn [and others] Screening for Epstein-Barr virus in Hodgkin's lymphoma / Gulfaraz Khan. A hepatitis C virus xenograft mouse efficacy model / Qing Zhu and Amy J. Weiner. Gene expression profiling in cervical cancer: identification of novel markers for disease diagnosis and therapy / Cara M. Martin [and others] Detection and genotyping analysis of human papillomavirus isolates from liquid- based cervical cytology specimens / Patricia Avissar and Douglas P. Malinowski.

Print version record.

According to the most recent clinical oncology data, one out of seven newly diagnosed malignancies worldwide result from infection and chronic inflammation in conjunction with cancer. In Inflammation and Cancer: Methods and Protocols, expert researchers deliver a systematic guide to techniques addressing various aspects of experimental cancer biology, selectively focused on inflammation-mediated tumorigenesis, while promoting improvisations on a per-case basis. Volume 1, Experimental Models and Practical Approaches provides an overview of a spectrum of techniques developed to analyze the outcomes of inflammation-mediated carcinogenesis on the tissue, cellular, and molecular levels while highlighting several diagnostic aspects, such as biomarker discovery and molecular signatures evaluation. Written in the highly successful Methods in Molecular Biology series format, chapters include brief introductions to their subjects, lists of the necessary materials and reagents, step-by-step laboratory protocols, and a notes section, which examines tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Inflammation and Cancer: Methods and Protocols promises to serve as a vital guide and resource for investigators and clinicians working toward the goal of combatting the estimated 2, 200 inflammation-related oncogenesis fatalities occurring every day.

English.

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