Peptide microarrays : methods and protocols / edited by Marina Cretich, Marcella Chiari.
Contributor(s): Cretich, Marina | Chiari, MarcellaMaterial type: TextSeries: Springer protocols (Series): ; Methods in molecular biology (Clifton, N.J.): v. 570.Publisher: New York, NY : Humana Press, ©2009Description: 1 online resource (xii, 433 pages) : illustrationsContent type: text Media type: computer Carrier type: online resourceISBN: 9781603273947; 1603273948Subject(s): Protein microarrays | Peptides -- analysis | Protein Array Analysis -- methods | Protein microarrays | Peptide | Microarray | Technischer Fortschritt | Datenanalyse | Peptides -- Analysis | Protein Array Analysis -- methods | Protein microarrays | Peptide | Microarray | Technischer Fortschritt | Datenanalyse | Animal Biochemistry | Human Anatomy & Physiology | Health & Biological Sciences | peptiden | peptides | moleculaire biologie | molecular biology | microarrays | Molecular Biology (General) | Moleculaire biologie (algemeen)Genre/Form: Laboratory Manual. | Electronic books. Additional physical formats: Print version:: Peptide microarrays.DDC classification: 612.015 LOC classification: QP551 | .P396 2009Other classification: Q51 Online resources: Click here to access online
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Includes bibliographical references and index.
Exploring and profiling protein function with peptide arrays / V.E. Tapia, B. Ay and R. Volkmer -- Peptide arrays for enzyme profiling / A. Thiele, J. Zerweck and M. Schutkowski -- Using peptide array to identify binding motifs and interaction networks for modular domains / S.S. Li and C. Wu -- Molecular simulations of peptides: a useful tool for the development of new drugs and for the study of molecular recognition / M. Meli and G. Colombo -- Synthesis of peptide arrays using SPOT-technology and the CelluSpots-method / D.F. Winkler [and others] -- Rapid identification of linear protein domain binding motifs using peptide SPOT arrays / D.J. Briant [and others] -- Characterization of kinase target phosphorylation consensus motifs using peptide SPOT arrays / G.C. Leung [and others] -- CelluSpots: a reproducible means of making peptide arrays for the determination of SH2 domain binding specificity / C. Wu and S.S. Li -- High-density peptide microarrays for reliable identification of phosphorylation sites and upstream kinases / A. Thiele [and others] -- Epitope mapping of human chromogranin A by peptide microarrays / M. Cretich [and others] -- Antimicrobial peptide arrays for detection of inactivated biothreat agents / C.R. Taitt, S.H. North and N.V. Kulagina -- Mapping functional prion-prion protein interaction sites using prion protein based peptide-arrays / A. Rigter [and others] -- A designed peptide chip: protein fingerprinting technology with a dry peptide array and statistical data mining / K. Usui, K.Y. Tomizaki and H. Mihara -- Peptide microarrays on bisphenol A polycarbonate / V. Souplet, C. Roux and O. Melnyk -- Self-assembly of PNA-encoded peptides into microarrays / F. Debaene and N. Winssinger -- A novel combinatorial approach to high-density peptide arrays / M. Beyer [and others] -- Polypyrrole-peptide microarray for biomolecular interaction analysis by SPR imaging / M.B. Villiers [and others] -- The peptide microarray-based assay for kinase functionality and inhibition study / Z. Wang -- An advanced application of protein microarrays: cell-based assays for functional genomics / R. Carbone -- Profiling the autoantibody repertoire by screening phage-displayed human cDNA libraries / R. Di Niro [and others] -- Visualisation and pre-processing of peptide microarray data / M. Reilly and D. Valentini -- Web-based design of peptide microarrays using microPepArray Pro / T. Li [and others] -- Qualitative and quantitative analysis of peptide microarray binding experiments using SVM-PEPARRAY / G. Chen [and others] -- PASE: a web-based platform for peptide/protein microarray experiments / F. Pamelard [and others].
Print version record.
Due to their versatility, along with the diminishing costs of library synthesis and the growth of commercial support, peptide microarrays will likely expand beyond being just a research tool into an adaptable and powerful platform to be harnessed for wider drug discovery and point-of-care applications. In Peptide Microarrays: Methods and Protocols, experts in the field provide a cutting-edge view of peptide array technology, its applications, and technical issues. After examining how peptides can characterize proteins and clarify, at the amino acid level, the molecular recognition events in which they are involved, the volume goes on to cover topics such as the production and use of peptide arrays for enzyme and binding motifs characterization, epitope mapping, and diagnostics, the newest technological advancements, as well as software and web tools for the design of peptide arrays and for the analysis of output data. As a volume in the highly successful Methods in Molecular Biology series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easy-to-use, Peptide Microarrays: Methods and Protocols promises to serve scientists with its unique insights and novel solutions in peptide array technology in order to advance this vital field.