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Suppression and regulation of immune responses : methods and protocols / edited by Maria Cristina Cuturi and Ignacio Anegon.

Contributor(s): Cuturi, Maria Cristina | Anegon, IgnacioMaterial type: TextTextSeries: Springer protocols (Series) | Methods in molecular biology (Clifton, N.J.) ; v. 677.Publication details: New York, N.Y. : Humana Press, ©2011. Description: 1 online resource (xviii, 473 pages) : illustrationsContent type: text Media type: computer Carrier type: online resourceISBN: 9781607618690; 1607618699Subject(s): Immune response -- Regulation | Immunosuppression | Immunotherapy | Biological Therapy | Immune System Phenomena | Lymphocytes | Immunologic Techniques | Phenomena and Processes | Leukocytes, Mononuclear | Investigative Techniques | Therapeutics | Immunomodulation | T-Lymphocytes | Immunosuppression | Analytical, Diagnostic and Therapeutic Techniques and Equipment | Leukocytes | Blood Cells | Immune System | Blood | Hemic and Immune Systems | Cells | Anatomy | Biology | Health & Biological Sciences | Microbiology & Immunology | Immunology | Immune response -- Regulation | Immunosuppression | immunologie | immunology | biomedische wetenschappen | biomedicine | Medicine (General) | Geneeskunde (algemeen)Genre/Form: Electronic books. Additional physical formats: Print version:: Suppression and regulation of immune responses.DDC classification: 616.07/9 LOC classification: QR186 | .S86 2011NLM classification: QW920Online resources: Click here to access online
Contents:
Natural and induced T CD4+CD25+FOXP3+ regulatory T cells / L. Chatenoud -- Polyclonal expansion of human CD4(+)CD25(+) regulatory T cells / P. Hoffmann, R. Eder and M. Edinger -- Methods for in vitro generation of human type 1 regulatory T cells / S. Gregori, M.G. Roncarolo and R. Bacchetta -- Ex vivo generation of regulatory T cells: Characterization and therapeutic evaluation in a model of chronic colitis / F. Karlsson [and others] -- Phenotypic and functional characterization of CD8(+) T regulatory cells / S. Menoret [and others] -- Regulatory CD4( -- )CD8( -- ) double negative T cells / E.Y. Kim, S.C. Juvet and L. Zhang -- Identifying regulatory B cells (B10 cells) that produce IL-10 in mice / T. Matsushita and T.F. Tedder -- DCs in immune tolerance in steady-state conditions / T. Fukaya [and others] -- Plasmacytoid dendritic cells in tolerance / E. Gehrie [and others] -- In vitro-generated DC with tolerogenic functions: Perspectives for in vivo cellular therapy / C. van Kooten and K.A. Gelderman -- Preparation of mouse bone marrow-derived dendritic cells with immunoregulatory properties / M. Segovia, M.C. Cuturi and M. Hill -- Myeloid-derived suppressor cells: Characterization and expansion in models of endotoxemia and transplantation / N. Van Rompaey and A. Le Moine -- Human regulatory macrophages / J.A. Hutchinson [and others] -- NKT and tolerance / J. Diana [and others] -- Antiinflammatory and immunosuppressive functions of mast cells / J. Kalesnikoff and S.J. Galli -- A mesenchymal stem cell potency assay / J. Jiao [and others] -- In vitro analyses of the immunosuppressive properties of neural stem/progenitor cells using anti-CD3/CD28-activated T cells / V. Bonnamain, I. Neveu and P. Naveilhan -- Immunoregulatory properties of heme oxygenase-1 / P. Blancou [and others] -- Indoleamine 2,3-dioxygenase and regulatory function: Tryptophan starvation and beyond / C. Orabona and U. Grohmann -- Regulatory T cell enrichment by IFN-[gamma] conditioning / G. Feng, K.J. Wood and A. Bushell -- Transforming growth factor-beta: Recent advances on its role in immune tolerance / P.Y. Mantel and C.B. Schmidt-Weber -- Induction of tolerogenic dendritic cells by NF-[kappa]b blockade and fcgamma receptor modulation / L.J. Carreno, C.A. Riedel and A.M. Kalergis -- Fine-tuning antitumor responses through the control of galectin-glycan interactions: An overview / M. Salatino and G.A. Rabinovich -- Regulation of lymphocytes by nitric oxide / C. Bogdan -- Pregnancy: Tolerance and suppression of immune responses / A. Leber [and others] -- Organ transplantation: Modulation of t-cell activation pathways initiated by cell surface receptors to suppress graft rejection / K. Weatherly and M.Y. Braun -- Immunosuppressive mechanisms during viral infectious diseases / G. Sarikonda and M.G. von Herrath -- Ocular immune privilege sites / S. Masli and J.L. Vega -- Immunoprivileged sites: The testis / M. Fijak, S. Bhushan and A. Meinhardt.
Summary: Over the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation. In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers highlight recent advances in the identification, characterization, and generation of regulatory cells not only of the T cell lineage but also of other origins such as B, NK, myeloid, and dendritic cells, as well as the role of several suppressive molecules in immunoregulation. Particular emphasis is placed on the characterization of the molecular mechanisms and the therapeutic applications of regulatory cells and molecules in human diseases. Written as a volume in the highly successful Methods in Molecular Biology series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Comprehensive and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.
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Includes bibliographical references and index.

Natural and induced T CD4+CD25+FOXP3+ regulatory T cells / L. Chatenoud -- Polyclonal expansion of human CD4(+)CD25(+) regulatory T cells / P. Hoffmann, R. Eder and M. Edinger -- Methods for in vitro generation of human type 1 regulatory T cells / S. Gregori, M.G. Roncarolo and R. Bacchetta -- Ex vivo generation of regulatory T cells: Characterization and therapeutic evaluation in a model of chronic colitis / F. Karlsson [and others] -- Phenotypic and functional characterization of CD8(+) T regulatory cells / S. Menoret [and others] -- Regulatory CD4( -- )CD8( -- ) double negative T cells / E.Y. Kim, S.C. Juvet and L. Zhang -- Identifying regulatory B cells (B10 cells) that produce IL-10 in mice / T. Matsushita and T.F. Tedder -- DCs in immune tolerance in steady-state conditions / T. Fukaya [and others] -- Plasmacytoid dendritic cells in tolerance / E. Gehrie [and others] -- In vitro-generated DC with tolerogenic functions: Perspectives for in vivo cellular therapy / C. van Kooten and K.A. Gelderman -- Preparation of mouse bone marrow-derived dendritic cells with immunoregulatory properties / M. Segovia, M.C. Cuturi and M. Hill -- Myeloid-derived suppressor cells: Characterization and expansion in models of endotoxemia and transplantation / N. Van Rompaey and A. Le Moine -- Human regulatory macrophages / J.A. Hutchinson [and others] -- NKT and tolerance / J. Diana [and others] -- Antiinflammatory and immunosuppressive functions of mast cells / J. Kalesnikoff and S.J. Galli -- A mesenchymal stem cell potency assay / J. Jiao [and others] -- In vitro analyses of the immunosuppressive properties of neural stem/progenitor cells using anti-CD3/CD28-activated T cells / V. Bonnamain, I. Neveu and P. Naveilhan -- Immunoregulatory properties of heme oxygenase-1 / P. Blancou [and others] -- Indoleamine 2,3-dioxygenase and regulatory function: Tryptophan starvation and beyond / C. Orabona and U. Grohmann -- Regulatory T cell enrichment by IFN-[gamma] conditioning / G. Feng, K.J. Wood and A. Bushell -- Transforming growth factor-beta: Recent advances on its role in immune tolerance / P.Y. Mantel and C.B. Schmidt-Weber -- Induction of tolerogenic dendritic cells by NF-[kappa]b blockade and fcgamma receptor modulation / L.J. Carreno, C.A. Riedel and A.M. Kalergis -- Fine-tuning antitumor responses through the control of galectin-glycan interactions: An overview / M. Salatino and G.A. Rabinovich -- Regulation of lymphocytes by nitric oxide / C. Bogdan -- Pregnancy: Tolerance and suppression of immune responses / A. Leber [and others] -- Organ transplantation: Modulation of t-cell activation pathways initiated by cell surface receptors to suppress graft rejection / K. Weatherly and M.Y. Braun -- Immunosuppressive mechanisms during viral infectious diseases / G. Sarikonda and M.G. von Herrath -- Ocular immune privilege sites / S. Masli and J.L. Vega -- Immunoprivileged sites: The testis / M. Fijak, S. Bhushan and A. Meinhardt.

Print version record.

Over the past several years, a high diversity of regulatory cells and suppressive molecules has taken centre stage in the field of immunoregulation. In Suppression and Regulation of Immune Responses: Methods and Protocols, expert researchers highlight recent advances in the identification, characterization, and generation of regulatory cells not only of the T cell lineage but also of other origins such as B, NK, myeloid, and dendritic cells, as well as the role of several suppressive molecules in immunoregulation. Particular emphasis is placed on the characterization of the molecular mechanisms and the therapeutic applications of regulatory cells and molecules in human diseases. Written as a volume in the highly successful Methods in Molecular Biology series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results. Comprehensive and cutting-edge, Suppression and Regulation of Immune Responses: Methods and Protocols serves as a key reference for scientists seeking a way toward greater control over the enormous power of the complex and vital immune system.

English.

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