Animal models of acute neurological injuries II. Injury and mechanistic assessments. Volume 1 / edited by Jun Chen [and others].

Contributor(s): Chen, Jun (Professor of neurology and pharmacology) [edt]
Material type: TextTextSeries: Springer protocols (Series): Publisher: New York : Humana Press : Springer, ©2012Description: 1 online resource (xviii, 724 pages) : illustrations (some color)Content type: text Media type: computer Carrier type: online resourceISBN: 9781617795763; 1617795763Other title: Injury and mechanistic assessments. Volume 1Subject(s): Nervous system -- Diseases -- Animal models -- Handbooks, manuals, etc | Nervous system -- Wounds and injuries -- Handbooks, manuals, etc | Nervous system -- Pathophysiology -- Animal models -- Handbooks, manuals, etc | Brain Injuries | Craniocerebral Trauma | Models, Animal | Spinal Injuries | Nervous system -- Diseases -- Animal models | Nervous system -- Wounds and injuries | biomedische wetenschappen | biomedicine | neurologie | neurology | neurowetenschap | neuroscience | diermodellen | animal models | Medicine (General) | Geneeskunde (algemeen)Genre/Form: Electronic books. | Handbooks and manuals. Additional physical formats: Print version:: Animal models of acute neurological injuries II : volume 1 / Injury and mechanistic assessments.DDC classification: 616.8072 LOC classification: RD593 | .A55 2012Online resources: Click here to access online
Contents:
Histopathological assessments of Animal Models of Cerebral Ischemia / Ami P. Raval and Bingren Hu -- Assessment of cell death : apoptosis, necrosis, or in between / Thomas Genetta, Ling Wei, and Shan Ping Yu -- Stereology and 3D volume analyses in nervous tissue / Rabindra P. Singh, Li Shen, and Feng C. Zhou -- Assessments of reactive astrogliosis following CNS injuries / Candace L. Floyd -- Physiological Assessment in Stroke Research / Casey Lee Hall [and others] -- EEG, Evoked Potential, and extracellular single-unit recordings in vivo / Jie Wu -- Intracellular recording in vivo and patch-clamp recording on brain slices / Ping Deng and Zao C. Xu -- Electrophysiological evaluation of synaptic plasticity in injured CNS / Xiaoming Jin -- Characterization of RNA / Marcel P. Van der Brug, Mar Matarin, and Taura L. Barr -- MicroRNA expression profiling of rat blood and brain tissues : TaqMan real-time PCR microRNA assays / Da-Zhi Liu, Bradley P. Ander, and Frank R. Sharp -- Protein analysis / Anthony Kian-Fong Liou and Jun Chen -- Application of zymographic methods to study matrix enzymes following traumatic brain injury / Lesley K. Harris [and others] -- Rodent behavioral assessment in the home cage using the SmartCage system / Xinmin Simon Xie [and others] -- Assessments of cognitive function following traumatic brain injury / Wendy M. Reid and Dong Sun -- Assessment of cognitive and sensorimotor deficits / Richard E. Hartman -- Emotional and anxiety assessments in CNS disorders / Zaorui Zhao and Junfang Wu -- Neuroimaging sssessment of traumatic brain injury / Janna L. Harris and William M. Brooks -- Imaging of myelin by coherent anti-stokes raman scattering microscopy / Yan Fu and Ji-Xin Cheng -- Grading scales for subarachnoid hemorrhage / Andrew Losiniecki and Mario Zuccarello -- Acute physiologic and morphologic assessment following subarachnoid hemorrhage / Vincent DiNapoli and Mario Zuccarello -- Aneurysmal subarachnoid hemorrhage grading in animal models / Robert Ayer, Takashi Sugawara, and John H. Zhang -- Physiological assessments of subarachnoid hemorrhage / Jens P. Dreier -- Spreading depolarization / Clemens Reiffurth, Sergei A. Kirov, and Jens P. Dreier -- Assessment of neurovascular coupling / Cecilia Nicoletti [and others] -- Assessment of global ischemia / Fatima A. Sehba and Joshua B. Bederson -- Assessment of microthromboembolism after subarachnoid hemorrhage / Mervyn D.I. Vergouwen and R. Loch Macdonald -- Intracranial pressure assessments / Carla S. Jung and Andreas W. Unterberg -- Assessment of blood-brain barrier breakdown / Yoash Chassidim [and others] -- Electrophysiology and morris water maze to assess hippocampal function after experimental subarachnoid hemorrhage / Asma Tariq and R. Loch Macdonald -- Biochemical and molecular biological assessments of subarachnoid hemorrhage / Joseph F. Clark -- Neurobehavioral assessments of subarachnoid hemorrhage / Hidenori Suzuki and John H. Zhang -- Neuroimaging assessment of subarachnoid hemorrhage / Andre Obenaus and Sam Barnes -- Introduction to problems of postsubarachnoid hemorrhage delayed cerebral vasospasm / Ryszard M. Pluta -- Morphological assessments of cerebral vasospasm / Hiroki Ohkuma -- Vasospasm : measurement of diameter, perimeter, and wall thickness / Mohammed Sabri and R. Loch Macdonald -- Light microscopic assessment / Akira Munakata, Norihito Shimamura, and Hiroki Ohkuma -- Electron microscopic assessment / Norihito Shimamura, Akira Munakata and Hiroki Ohkuma -- Morphological assessment of microcirculation / Hiroki Ohkuma and Shigeharu Suzuki -- Electrophysiological assessment of cerebral vasospasm / Jinglu Ai and R. Loch Macdonald -- Cranial window assessments in experimental aSAH in mice / Ulf C. Schneider, Etienne N. Atangana, and Peter Vajkoczy -- Laser Speckle Imaging / Nils Hecht [and others] -- Ion Channel Assessment / Marcel Alexander Kamp, Hans-Jakob Steiger, and Daniel Hanggi -- Biochemical assessments of cerebral vasospasm : measurement of cGMP, PKC, and PTK in cerebral arteries / Masayo Koide and Shigeru Nishizawa -- Assessment of intracellular calcium in cerebral artery myocytes / Matthew A. Nystoriak, Masayo Koide, and George C. Wellman -- Neurobehavioral assessments of cerebral vasospasm / Ryszard M. Pluta, Boris Skopets, and Jerald D. Kralik -- Neuroimaging assessment of cerebral vasospasm / Kaisorn L. Chaichana, Gustavo Pradilla, and Rafael J. Tamargo -- Morphological assessment of intracerebral hemorrhage / Qing Xie, Guohua Xi, and Ya Hua -- Immunological response to experimental intracerebral hemorrhage : morphological assessments / Elena Titova and Andre Obenaus -- Intracranial pressure assessment / Yangdong He, Ya Hua, and Guohua Xi -- Hemoglobin measurements / Yangdong He, Ya Hua, and Guohua Xi -- Biochemical and molecular biological assessments of intracerebral hemorrhage / Jin-Yul Lee [and others] -- Neurobehavioral assessments of intracerebral hemorrhage / Tim Lekic, and John H Zhang -- Corner turning test for evaluation of asymmetry after intracerebral hemorrhage in rodents / Tim Lekic [and others] -- Forelimb use asymmetry analysis of vertical exploratory activity after intracerebral hemorrhage in rats and mice / Tim Lekic [and others] -- Vibrissae-elicited forelimb placing test after intracerebral hemorrhage in rodents / Tim Lekic [and others] -- Imaging of hematoma and perihematomal edema in experimental intracerebral hemorrhage / Veit Rohde, Walter Schulz-Schaffer, and Timo Krings.
Summary: The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries. Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system. Volume 1 examines general assessments in morphology, physiology, biochemistry and molecular biology, neurobehavior, and neuroimaging, as well as extensive sections on subarachnoid hemorrhage, cerebral vasospasm, and intracerebral hemorrhage. Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used. Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.
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Histopathological assessments of Animal Models of Cerebral Ischemia / Ami P. Raval and Bingren Hu -- Assessment of cell death : apoptosis, necrosis, or in between / Thomas Genetta, Ling Wei, and Shan Ping Yu -- Stereology and 3D volume analyses in nervous tissue / Rabindra P. Singh, Li Shen, and Feng C. Zhou -- Assessments of reactive astrogliosis following CNS injuries / Candace L. Floyd -- Physiological Assessment in Stroke Research / Casey Lee Hall [and others] -- EEG, Evoked Potential, and extracellular single-unit recordings in vivo / Jie Wu -- Intracellular recording in vivo and patch-clamp recording on brain slices / Ping Deng and Zao C. Xu -- Electrophysiological evaluation of synaptic plasticity in injured CNS / Xiaoming Jin -- Characterization of RNA / Marcel P. Van der Brug, Mar Matarin, and Taura L. Barr -- MicroRNA expression profiling of rat blood and brain tissues : TaqMan real-time PCR microRNA assays / Da-Zhi Liu, Bradley P. Ander, and Frank R. Sharp -- Protein analysis / Anthony Kian-Fong Liou and Jun Chen -- Application of zymographic methods to study matrix enzymes following traumatic brain injury / Lesley K. Harris [and others] -- Rodent behavioral assessment in the home cage using the SmartCage system / Xinmin Simon Xie [and others] -- Assessments of cognitive function following traumatic brain injury / Wendy M. Reid and Dong Sun -- Assessment of cognitive and sensorimotor deficits / Richard E. Hartman -- Emotional and anxiety assessments in CNS disorders / Zaorui Zhao and Junfang Wu -- Neuroimaging sssessment of traumatic brain injury / Janna L. Harris and William M. Brooks -- Imaging of myelin by coherent anti-stokes raman scattering microscopy / Yan Fu and Ji-Xin Cheng -- Grading scales for subarachnoid hemorrhage / Andrew Losiniecki and Mario Zuccarello -- Acute physiologic and morphologic assessment following subarachnoid hemorrhage / Vincent DiNapoli and Mario Zuccarello -- Aneurysmal subarachnoid hemorrhage grading in animal models / Robert Ayer, Takashi Sugawara, and John H. Zhang -- Physiological assessments of subarachnoid hemorrhage / Jens P. Dreier -- Spreading depolarization / Clemens Reiffurth, Sergei A. Kirov, and Jens P. Dreier -- Assessment of neurovascular coupling / Cecilia Nicoletti [and others] -- Assessment of global ischemia / Fatima A. Sehba and Joshua B. Bederson -- Assessment of microthromboembolism after subarachnoid hemorrhage / Mervyn D.I. Vergouwen and R. Loch Macdonald -- Intracranial pressure assessments / Carla S. Jung and Andreas W. Unterberg -- Assessment of blood-brain barrier breakdown / Yoash Chassidim [and others] -- Electrophysiology and morris water maze to assess hippocampal function after experimental subarachnoid hemorrhage / Asma Tariq and R. Loch Macdonald -- Biochemical and molecular biological assessments of subarachnoid hemorrhage / Joseph F. Clark -- Neurobehavioral assessments of subarachnoid hemorrhage / Hidenori Suzuki and John H. Zhang -- Neuroimaging assessment of subarachnoid hemorrhage / Andre Obenaus and Sam Barnes -- Introduction to problems of postsubarachnoid hemorrhage delayed cerebral vasospasm / Ryszard M. Pluta -- Morphological assessments of cerebral vasospasm / Hiroki Ohkuma -- Vasospasm : measurement of diameter, perimeter, and wall thickness / Mohammed Sabri and R. Loch Macdonald -- Light microscopic assessment / Akira Munakata, Norihito Shimamura, and Hiroki Ohkuma -- Electron microscopic assessment / Norihito Shimamura, Akira Munakata and Hiroki Ohkuma -- Morphological assessment of microcirculation / Hiroki Ohkuma and Shigeharu Suzuki -- Electrophysiological assessment of cerebral vasospasm / Jinglu Ai and R. Loch Macdonald -- Cranial window assessments in experimental aSAH in mice / Ulf C. Schneider, Etienne N. Atangana, and Peter Vajkoczy -- Laser Speckle Imaging / Nils Hecht [and others] -- Ion Channel Assessment / Marcel Alexander Kamp, Hans-Jakob Steiger, and Daniel Hanggi -- Biochemical assessments of cerebral vasospasm : measurement of cGMP, PKC, and PTK in cerebral arteries / Masayo Koide and Shigeru Nishizawa -- Assessment of intracellular calcium in cerebral artery myocytes / Matthew A. Nystoriak, Masayo Koide, and George C. Wellman -- Neurobehavioral assessments of cerebral vasospasm / Ryszard M. Pluta, Boris Skopets, and Jerald D. Kralik -- Neuroimaging assessment of cerebral vasospasm / Kaisorn L. Chaichana, Gustavo Pradilla, and Rafael J. Tamargo -- Morphological assessment of intracerebral hemorrhage / Qing Xie, Guohua Xi, and Ya Hua -- Immunological response to experimental intracerebral hemorrhage : morphological assessments / Elena Titova and Andre Obenaus -- Intracranial pressure assessment / Yangdong He, Ya Hua, and Guohua Xi -- Hemoglobin measurements / Yangdong He, Ya Hua, and Guohua Xi -- Biochemical and molecular biological assessments of intracerebral hemorrhage / Jin-Yul Lee [and others] -- Neurobehavioral assessments of intracerebral hemorrhage / Tim Lekic, and John H Zhang -- Corner turning test for evaluation of asymmetry after intracerebral hemorrhage in rodents / Tim Lekic [and others] -- Forelimb use asymmetry analysis of vertical exploratory activity after intracerebral hemorrhage in rats and mice / Tim Lekic [and others] -- Vibrissae-elicited forelimb placing test after intracerebral hemorrhage in rodents / Tim Lekic [and others] -- Imaging of hematoma and perihematomal edema in experimental intracerebral hemorrhage / Veit Rohde, Walter Schulz-Schaffer, and Timo Krings.

Includes bibliographical references and index.

Print version record.

The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries. Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system. Volume 1 examines general assessments in morphology, physiology, biochemistry and molecular biology, neurobehavior, and neuroimaging, as well as extensive sections on subarachnoid hemorrhage, cerebral vasospasm, and intracerebral hemorrhage. Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used. Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.

English.

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