Microdialysis techniques in neuroscience / edited by Giuseppe Di Giovanni, Vincenzo Di Matteo.

Contributor(s): Di Giovanni, Giuseppe | Di Matteo, Vincenzo
Material type: TextTextSeries: Neuromethods: 75.; Springer protocols (Series): Publisher: New York : Humana Press : Springer, ©2013Description: 1 online resource (xvii, 341 pages) : illustrations (some color)Content type: text Media type: computer Carrier type: online resourceISBN: 9781627031738; 1627031731Subject(s): Brain microdialysis | Microdialysis -- methods | Neurosciences | Brain microdialysis | biomedische wetenschappen | biomedicine | neurowetenschap | neuroscience | neurobiologie | neurobiology | Medicine (General) | Geneeskunde (algemeen)Genre/Form: Electronic books. Additional physical formats: Print version:: Microdialysis techniques in neuroscience.DDC classification: 612.8/042 LOC classification: QP356.3 | .M53 2013Online resources: Click here to access online
Contents:
Cerebral microdialysis : research technique or clinical tool? / Anouk Borg and Martin Smith -- In vivo microdialysis to study striatal dopaminergic neurodegeneration / Giuseppe Di Giovanni [and others] -- Application of reverse microdialysis in neuropharmacological studies / Christian Hocht, Facundo Martin Bertera, and Carlos Alberto Taira -- Microdialysis and advances for sampling synaptic and extrasynaptic pools / Cheng-fu Chen [and others] -- In vivo microdialysis for measurement of oxidative metabolism in the living brain / H. Ronald Zielke, Carol L. Zielke, and Peter J. Baab -- Quantitative in vivo microdialysis in pharmacokinetic studies / Teodoro Zornoza [and others] -- Combination of in vivo microdialysis with selective electrochemical detection for online continuous monitoring of brain chemistry / Yuqing Lin, Zipin Zhang, and Lanqun Mao -- Application of spinal microdialysis in freely moving rats / Vincent Umbrain [and others] -- Monitoring extracellular monoamines with in vivo microdialysis in awake rats : a practical approach / Roberto W. Invernizzi -- Intracerebral Human Microdialysis in Parkinson's Disease / Salvatore Galati and Giuseppe Di Giovanni -- Monitoring extracellular amino acid neurotransmitters and hROS by in vivo microdialysis in rats : a practical approach / Maria Alessandra Colivicchi [and others] -- Measurement of neuropeptides in dialysate by LC-MS / Omar S. Mabrouk and Robert T. Kennedy -- Achieving high temporal resolution for in vivo measurements by microdialysis / Neil D. Hershey and Robert T. Kennedy -- Indirect analysis of nitric oxide and quantitation of selective nitric oxide synthase inhibitors in microdialysate samples / Gary M. Pollack -- Determination of histamine in microdialysis samples from the rodent brain by column liquid chromatography / Jan Kehr and Takashi Yoshitake -- Intracerebral microdialysis in the study of limbic seizure mechanisms and antiepileptic drug action using freely moving rats / Jeanelle Portelli and Ilse Smolders.
Summary: Since its first application, microdialysis has become incredibly popular to study brain function and has been applied with success in different fields from psychopharmacology, neurobiology, and physiology in animals and also humans. Microdialysis Techniques in Neuroscience focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain. The book's contents range from new techniques for detection and quantifying the release of several different neurotransmitters in vitro and in vivo, even in freely moving animals, to sophisticated use of reverse dialysis and the application of microdialysis in pharmacokinetic studies. Each of the sixteen chapters, in fitting with the spirit of the Neuromethods series, contain an introduction that gives a broad overview of a focused topic, followed by an extensive protocol on how the experiments are performed along with invaluable practical advice. Detailed and authoritative, Microdialysis Techniques in Neuroscience will be a valuable reference for students, neuroscientists, and physicians for the use of microdialysis in the study of brain functions and its clinical applications.
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Cerebral microdialysis : research technique or clinical tool? / Anouk Borg and Martin Smith -- In vivo microdialysis to study striatal dopaminergic neurodegeneration / Giuseppe Di Giovanni [and others] -- Application of reverse microdialysis in neuropharmacological studies / Christian Hocht, Facundo Martin Bertera, and Carlos Alberto Taira -- Microdialysis and advances for sampling synaptic and extrasynaptic pools / Cheng-fu Chen [and others] -- In vivo microdialysis for measurement of oxidative metabolism in the living brain / H. Ronald Zielke, Carol L. Zielke, and Peter J. Baab -- Quantitative in vivo microdialysis in pharmacokinetic studies / Teodoro Zornoza [and others] -- Combination of in vivo microdialysis with selective electrochemical detection for online continuous monitoring of brain chemistry / Yuqing Lin, Zipin Zhang, and Lanqun Mao -- Application of spinal microdialysis in freely moving rats / Vincent Umbrain [and others] -- Monitoring extracellular monoamines with in vivo microdialysis in awake rats : a practical approach / Roberto W. Invernizzi -- Intracerebral Human Microdialysis in Parkinson's Disease / Salvatore Galati and Giuseppe Di Giovanni -- Monitoring extracellular amino acid neurotransmitters and hROS by in vivo microdialysis in rats : a practical approach / Maria Alessandra Colivicchi [and others] -- Measurement of neuropeptides in dialysate by LC-MS / Omar S. Mabrouk and Robert T. Kennedy -- Achieving high temporal resolution for in vivo measurements by microdialysis / Neil D. Hershey and Robert T. Kennedy -- Indirect analysis of nitric oxide and quantitation of selective nitric oxide synthase inhibitors in microdialysate samples / Gary M. Pollack -- Determination of histamine in microdialysis samples from the rodent brain by column liquid chromatography / Jan Kehr and Takashi Yoshitake -- Intracerebral microdialysis in the study of limbic seizure mechanisms and antiepileptic drug action using freely moving rats / Jeanelle Portelli and Ilse Smolders.

Includes bibliographical references and index.

Print version record.

Since its first application, microdialysis has become incredibly popular to study brain function and has been applied with success in different fields from psychopharmacology, neurobiology, and physiology in animals and also humans. Microdialysis Techniques in Neuroscience focuses on the practical aspects of microdialysis in animal and human, highlighting current technical limitations and providing a vision of what is yet to come for the determination of the most disparate compounds in the brain. The book's contents range from new techniques for detection and quantifying the release of several different neurotransmitters in vitro and in vivo, even in freely moving animals, to sophisticated use of reverse dialysis and the application of microdialysis in pharmacokinetic studies. Each of the sixteen chapters, in fitting with the spirit of the Neuromethods series, contain an introduction that gives a broad overview of a focused topic, followed by an extensive protocol on how the experiments are performed along with invaluable practical advice. Detailed and authoritative, Microdialysis Techniques in Neuroscience will be a valuable reference for students, neuroscientists, and physicians for the use of microdialysis in the study of brain functions and its clinical applications.

English.

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