Methionine dependence of cancer and aging : methods and protocols / edited by Robert M. Hoffman.
Contributor(s): Hoffman, Robert M [editor.]Material type: TextSeries: Methods in molecular biology (Clifton, N.J.): v. 1866.Publisher: New York, NY : Humana Press : Springer, Copyright date: ©2019Description: 1 online resource (xii, 329 pages) : illustrations (some color)Content type: text Media type: computer Carrier type: online resourceISBN: 9781493987962; 1493987968Subject(s): Methionine | Cancer -- Molecular aspects | Cancer -- Chemotherapy | Methionine | Neoplasms -- metabolism | Aging | Cancer -- Chemotherapy | Cancer -- Molecular aspects | MethionineGenre/Form: Laboratory Manual. | Electronic books. Additional physical formats: Print version:: Methionine dependence of cancer and aging .DDC classification: 572/.65 LOC classification: QP562.M4 | M48 2019Online resources: Click here to access online
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Includes bibliographical references and index.
Methods to study the role of methionine-restricted diet and methioninase in cancer growth control / Shushma Chaturvedi and Joseph R. Bertino -- Altered methionine metabolism in cancer cells / Robert M. Hoffman, Peter H. Stern, DennisW. Coalson, C. DouglasWallace, and Richard W. Erbe -- Linkage of methionine dependence and other features of malignancy / Robert M. Hoffman and Richard W. Erbe -- Isolation and characterization of methionine-independent clones from methionine-dependent cancer cells / Stacey L. Borrego, Da-Wei Lin, and Peter Kaiser -- Tumor-specific S/G2-phase cell cycle arrest of cancer cells by methionine restriction / Robert M. Hoffman and Shuya Yano -- Preclinical breast cancer models to investigate metabolic priming by methionine restriction / Elena Strekalova, Dmitry Malin, Harisha Rajanala, and Vincent L. Cryns -- Efficacy of methionine-restricted diets on cancers in vivo / Robert M. Hoffman, Yasunori Hoshiya, and Weiyan Guo -- Dietary methionine restriction-based cancer chemotherapy in rodents / Robert M. Hoffman and Peter H. Stern -- Clinical studies of methionine-restricted diets for cancer patients / Robert M. Hoffman -- Development of recombinant methioninase for cancer treatment / Robert M. Hoffman, Yuying Tan, Shukuan Li, Qinghong Han, Shigeo Yagi, Tomoaki Takakura, Akio Takimoto, Kenji Inagaki, and Daizou Kudou -- Methioninase cell-cycle trap cancer chemotherapy / Robert M. Hoffman, Shuya Yano, and Kentaro Igarashi -- High efficacy of recombinant methioninase on patient-derived orthotopic xenograft (PDOX) mouse models of cancer / Robert M. Hoffman, Takashi Murakami, Kei Kawaguchi, Kentaro Igarashi, Yuying Tan, Shukuan Li, and Qinghong Han -- Total methionine restriction treatment of cancer / Robert M. Hoffman, Demetrius M. Kokkinakis, and Eugene P. Frenkel -- Methioninase gene therapy / Robert M. Hoffman, Kenji Miki, Waddah Al-Refaie, Mingxu Xu, and Yuying Tan -- Selenomethionine and methioninase : selenium free radical anticancer activity / Julian E. Spallholz -- Safety and toxicity of recombinant methioninase and polyethylene glycol (PEG) recombinant methioninase in primates / Robert M. Hoffman, Zhijian Yang, Yuying Tan, Qinghong Han, Shukuan Li, and Shigeo Yagi -- Pilot phase I clinical trial of methioninase on high-stage cancer patients : rapid depletion of circulating methionine / Robert M. Hoffman, Yuying Tan, Shukuan Li, Qinghong Han, Jorge Zavala Sr, and Jorge Zavala Jr -- Methionine gamma lyase from Clostridium sporogenes increases the anticancer efficacy of doxorubicin on A549 cancer cells in vitro and human cancer xenografts / V.S. Pokrovsky, N. Yu. Anisimova, D. Zh. Davydov, S.V. Bazhenov, N.V. Bulushova, G.B. Zavilgelsky, V.Y. Kotova, and I.V. Manukhov -- Methionine restriction and life-span extension / Robert M. Hoffman -- L-[Methyl-11C] methionine-positron-emission tomography (MET-PET) / Robert M. Hoffman -- Is the Hoffman effect for methionine overuse analogous to the warburg effect for glucose overuse in cancer? / Robert M. Hoffman -- Recombinant methioninase as a DNA demethylation agent / Robert M. Hoffman and David Machover -- Homocysteine, thioretinaco ozonide, and oxidative phosphorylation in cancer and aging : a proposed clinical trial protocol / Kilmer S. McCully -- Afterword : oral methioninase--answer to cancer and fountain of youth? / Robert M. Hoffman, Qinghong Han, Kei Kawaguchi, Shukuan Li, and Yuying Tan -- Epilogue : why do we keep mis-targeting cancer chemotherapy when the methionine target has been obvious for more than a half-century?
Online resource; title from PDF title page (SpringerLink, viewed February 6, 2019).