Glaucoma : an open window to neurodegeneration and neuroprotection / edited by Carlo Nucci, Neville N. Osborne, Giacinto Bagetta, Luciano Cerulli.

Contributor(s): Nucci, Carlo [editor.] | Cerulli, Luciano [editor.] | Osborne, Neville N [editor.] | Bagetta, Giacinto [editor.]
Material type: TextTextSeries: Progress in brain research: v. 173.Publisher: Amsterdam ; London : Elsevier, 2008Edition: 1. editionDescription: 1 online resource (xvi, 622 pages, 16 pages of plates) : illustrations (some color)Content type: text Media type: computer Carrier type: online resourceISBN: 9780080932804; 0080932800; 9780444532565; 0444532560Subject(s): Glaucoma -- Diagnosis | Glaucoma -- Treatment | Glaucoma -- Monitoring | Retinal ganglion cells -- Monitoring | Intraocular pressure -- Monitoring | Glaucoma -- physiopathology | Glaucoma -- therapy | Nerve Degeneration -- prevention & control | Nerve Tissue Proteins -- physiology | Neuroprotective Agents -- pharmacology | MEDICAL -- Ophthalmology | HEALTH & FITNESS -- Vision | Glaucoma -- Diagnosis | Glaucoma -- Treatment | Glaucoom | NeuropathologieGenre/Form: Electronic books. Additional physical formats: Print version:: Glaucoma.DDC classification: 617.7/41 LOC classification: RE871 | .G53 2008ebOther classification: 44.95 | 44.90 Online resources: Click here to access online
Contents:
Epidemiology of primary glaucoma: prevalence, incidence, and blinding effects -- Predictive models to estimate the risk of glaucoma development and progression -- Intraocular pressure and central corneal thickness -- Angle-closure: risk factors, diagnosis and treatment -- Early diagnosis of glaucoma -- Monitoring glaucoma progression -- Standard automated perimetry and algorithms for monitoring glaucoma progression -- Short-wavelength automated perimetry and frequency-doubling technology perimetry in glaucoma -- Scanning laser polarimetry and confocal scanning laser ophthalmoscopy: technical notes on their use in glaucoma -- The role of OCT in glaucoma management -- Functional laser Doppler flowmetry of the optic nerve: physiological aspects and clinical applications -- Advances in neuroimaging of the visual pathways and their use in glaucoma -- Primary open angle glaucoma: an overview of medical therapy -- The treatment of normal-tension glaucoma -- The management of exfoliative glaucoma -- Laser therapies for glaucoma: new frontiers -- Modulation of wound healing during and after glaucoma surgery -- Surgical alternative to trabeculectomy -- Modern aqueous shunt implantation: future challenges -- Rat models for glaucoma research -- Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection -- Clinical trials in neuroprotection.
Pathogenesis of ganglion "cell death" in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria -- Astrocytes in glaucomatous optic neuropathy -- Glaucoma as a neuropathy amenable to neuroprotection and immune manipulation -- Oxidative stress and glaucoma: injury in the anterior segment of the eye -- TNF-alpha signaling in glaucomatous neurodegeneration -- Involvement of the Bc12 gene family in the signaling and control of retinal ganglion cell death -- Assessment of neuroprotection in the retina with DARC -- Potential roles of (endo)cannabinoids in the treatment of glaucoma: from intraocular pressure control to neuroprotection -- Glaucoma of the brain: a disease model for the study of transsynaptic neural degeneration -- Changes of central visual receptive fields on experimental glaucoma -- Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma -- Stem cells for neuroprotection in glaucoma -- The relationship between neurotrophic factors and CaMKII in the death and survival of retinal ganglion cells -- Evidence of the neuroprotective role of citicoline in glaucoma patients -- Neuroprotection: VEGF, IL-6, and clusterin: the dark side of the moon -- Rational basis for the development of coenzyme Q10 as a neurotherapeutic agent for retinal protection -- 17Beta-estradiol prevents retinal ganglion cell loss induced by the acute rise of intraocular pressure in rat.
Summary: An in-depth examination on risk factors, diagnosis, clinical monitoring and treatment of glaucoma.
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Includes bibliographical references and index.

1. Epidemiology of primary glaucoma: prevalence, incidence, and blinding effects -- 2. Predictive models to estimate the risk of glaucoma development and progression -- 3. Intraocular pressure and central corneal thickness -- 4. Angle-closure: risk factors, diagnosis and treatment -- 5. Early diagnosis of glaucoma -- 6. Monitoring glaucoma progression -- 7. Standard automated perimetry and algorithms for monitoring glaucoma progression -- 8. Short-wavelength automated perimetry and frequency-doubling technology perimetry in glaucoma -- 9. Scanning laser polarimetry and confocal scanning laser ophthalmoscopy: technical notes on their use in glaucoma -- 10. The role of OCT in glaucoma management -- 11. Functional laser Doppler flowmetry of the optic nerve: physiological aspects and clinical applications -- 12. Advances in neuroimaging of the visual pathways and their use in glaucoma -- 13. Primary open angle glaucoma: an overview of medical therapy -- 14. The treatment of normal-tension glaucoma -- 15. The management of exfoliative glaucoma -- 16. Laser therapies for glaucoma: new frontiers -- 17. Modulation of wound healing during and after glaucoma surgery -- 18. Surgical alternative to trabeculectomy -- 19 Modern aqueous shunt implantation: future challenges -- 20. Model systems for experimental studies: retinal ganglion cells in culture -- 21. Rat models for glaucoma research -- 22. Mouse genetic models: an ideal system for understanding glaucomatous neurodegeneration and neuroprotection -- 23. Clinical trials in neuroprotection.

24. Pathogenesis of ganglion "cell death" in glaucoma and neuroprotection: focus on ganglion cell axonal mitochondria -- 25. Astrocytes in glaucomatous optic neuropathy -- 26. Glaucoma as a neuropathy amenable to neuroprotection and immune manipulation -- 27. Oxidative stress and glaucoma: injury in the anterior segment of the eye -- 28 TNF-alpha signaling in glaucomatous neurodegeneration -- 29. Involvement of the Bc12 gene family in the signaling and control of retinal ganglion cell death -- 30. Assessment of neuroprotection in the retina with DARC -- 31. Potential roles of (endo)cannabinoids in the treatment of glaucoma: from intraocular pressure control to neuroprotection -- 32. Glaucoma of the brain: a disease model for the study of transsynaptic neural degeneration -- 33. Changes of central visual receptive fields on experimental glaucoma -- 34. Targeting excitotoxic/free radical signaling pathways for therapeutic intervention in glaucoma -- Stem cells for neuroprotection in glaucoma -- 36. The relationship between neurotrophic factors and CaMKII in the death and survival of retinal ganglion cells -- 37. Evidence of the neuroprotective role of citicoline in glaucoma patients -- 38. Neuroprotection: VEGF, IL-6, and clusterin: the dark side of the moon -- 39. Rational basis for the development of coenzyme Q10 as a neurotherapeutic agent for retinal protection -- 40. 17Beta-estradiol prevents retinal ganglion cell loss induced by the acute rise of intraocular pressure in rat.

An in-depth examination on risk factors, diagnosis, clinical monitoring and treatment of glaucoma.

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