Autonomic dysfunction after spinal cord injury / edited by Lynne C. Weaver, Canio Polosa.

Contributor(s): Weaver, Lynne C. (Lynne Christine), 1945- | Polosa, C. (Canio)
Material type: TextTextSeries: Progress in brain research: v. 152.Publisher: Amsterdam ; Boston : Elsevier, 2006Edition: 1st edDescription: 1 online resource (xviii, 453 pages) : illustrations (some color)Content type: text Media type: computer Carrier type: online resourceISBN: 0080460100; 9780080460109; 0444519254; 9780444519252Subject(s): Spinal cord -- Wounds and injuries -- Complications | Autonomic nervous system -- Diseases | Moelle épinière -- Lésions et blessures -- Complications et séquelles | Système nerveux autonome -- Maladies | MEDICAL -- Surgery -- Neurosurgery | Autonomic nervous system -- Diseases | Spinal cord -- Wounds and injuries -- Complications | Ruggenmerg | Beschadigingen | Autonoom zenuwstelsel | Spinal Cord Injuries -- complications | Autonomic Nervous System Diseases -- etiologyGenre/Form: Electronic books. Additional physical formats: Print version:: Autonomic dysfunction after spinal cord injuryDDC classification: 617.4/82044 LOC classification: RD594.3 | .A88 2006ebOther classification: 44.90 Online resources: Click here to access online
Contents:
Overview: autonomic dysfunction in spinal cord injury: clinical presentation of symptoms and signs / A.-K. Karlsson -- Anatomical changes mediating autonomic dysfunction after cord injury. Effects of spinal cord injury on synaptic inputs to sympathetic preganglionic neurons / I.J. Llewellyn-Smith, L.C. Weaver, and J.R. Keast. Spinal sympathetic interneurons: their identification and roles after spinal cord injury / L.P. Schramm. Which pathways must be spared in the injured human spinal cord to retain cardiovascular control? / A. Krassioukov -- Urinary bladder dysfunction. Disordered control of the urinary bladder after human spinal cord injury: what are the problems? / P.J. Potter. Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury / W.C. de Groat and N. Yoshimura. Spinal mechanisms contributing to urethral striated sphincter control during continence and micturition: how good things might go bad / S.J. Shefchyk. Neurochemical plasticity and the role of neurotrophic factors in bladder reflex pathways after spinal cord injury / M.A. Vizzard. Effect of injury severity on lower urinary tract function after experimental spinal cord injury / J.R. Wrathall and G.S. Emch. Role of the urothelium in urinary bladder dysfunction following spinal cord injury / L.A. Birder. Plasticity in the injured spinal cord: can we use it to advantage to reestablish effective bladder voiding and continence? / N.D.T. Zinck and J.W. Downie. Control of urinary bladder function with devices: successes and failures / R.A. Gaunt and A. Prochazka. Novel repair strategies to restore bladder function following cauda equina /conus medullaris injuries / T.X. Hoang and L.A. Havton. Pelvic somato-visceral reflexes after spinal cord injury: measures of functional loss and partial preservation / M.D. Craggs -- Cardiovascular dysfunction. The clinical problems in cardiovascular control following spinal cord injury: an overview / A. Krassioukov and V.E. Claydon. Orthostatic hypotension and paroxysmal hypertension in humans with high spinal cord injury / C.J. Mathias. Autonomic dysreflexia after spinal cord injury: central mechanisms and strategies for prevention / L.C. Weaver [and others] Segmental organization of spinal reflexes mediating autonomic dysreflexia after spinal cord injury / A.G. Rabchevsky. Spinal cord injury alters cardiac electrophysiology and increases the susceptibility to ventricular arrhythmias / H.L. Collins, D.W. Rodenbaugh, and S.E. DiCarlo. Adaptations of peripheral vasoconstrictor pathways after spinal cord injury / E.M. McLachlan and J.A. Brock. Genetic approaches to autonomic dysreflexia / A. Brown and J.E. Jacob -- Bowel dysfunction. Gastrointestinal symptoms related to autonomic dysfunction following spinal cord injury / E.A.L. Chung and A.V. Emmanuel. Colorectal motility and defecation after spinal cord injury in humans / A.C. Lynch and F.A. Frizelle. Mechanisms controlling normal defecation and the potential effects of spinal cord injury / A.F. Brading and T. Ramalingam. Alterations in eliminative and sexual reflexes after spinal cord injury: defecatory function and development of spasticity in pelvic floor musculature / Y.S. Nout [and others] Upper and lower gastrointestinal motor and sensory dysfunction after human spinal cord injury / P. Enck [and others] -- Sexual dysfunction. Problems of sexual function after spinal cord injury / S.L. Elliott. Ascending spinal pathways from sexual organs: effects of chronic spinal lesions / C.H. Hubscher. Descending pathways modulating the spinal circuitry for ejaculation: effects of chronic spinal cord injury / R.D. Johnson. Male fertility and sexual function after spinal cord injury / D.J. Brown, S.T. Hill, and H.W.G. Baker. Female sexual function after spinal cord injury / M.S. Sipski and A. Arenas.
Action note: digitized 2010 committed to preserveSummary: Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions. The book begins with a description of the time course of autonomic dysfunctions and their ramifications from the first hours after a spinal cord injury to the more stable chronic states. The next section contains three chapters that address anatomical findings that may provide some of the foundation for autonomic dysfunctions in many of the systems. The system-specific chapters then follow in four sections. Each section begins with a chapter or two defining the clinical problems experienced by people with cord injury. The following chapters present research, basic and clinical, that address the autonomic dysfunctions.
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Includes bibliographical references and index.

Overview: autonomic dysfunction in spinal cord injury: clinical presentation of symptoms and signs / A.-K. Karlsson -- Anatomical changes mediating autonomic dysfunction after cord injury. Effects of spinal cord injury on synaptic inputs to sympathetic preganglionic neurons / I.J. Llewellyn-Smith, L.C. Weaver, and J.R. Keast. Spinal sympathetic interneurons: their identification and roles after spinal cord injury / L.P. Schramm. Which pathways must be spared in the injured human spinal cord to retain cardiovascular control? / A. Krassioukov -- Urinary bladder dysfunction. Disordered control of the urinary bladder after human spinal cord injury: what are the problems? / P.J. Potter. Mechanisms underlying the recovery of lower urinary tract function following spinal cord injury / W.C. de Groat and N. Yoshimura. Spinal mechanisms contributing to urethral striated sphincter control during continence and micturition: how good things might go bad / S.J. Shefchyk. Neurochemical plasticity and the role of neurotrophic factors in bladder reflex pathways after spinal cord injury / M.A. Vizzard. Effect of injury severity on lower urinary tract function after experimental spinal cord injury / J.R. Wrathall and G.S. Emch. Role of the urothelium in urinary bladder dysfunction following spinal cord injury / L.A. Birder. Plasticity in the injured spinal cord: can we use it to advantage to reestablish effective bladder voiding and continence? / N.D.T. Zinck and J.W. Downie. Control of urinary bladder function with devices: successes and failures / R.A. Gaunt and A. Prochazka. Novel repair strategies to restore bladder function following cauda equina /conus medullaris injuries / T.X. Hoang and L.A. Havton. Pelvic somato-visceral reflexes after spinal cord injury: measures of functional loss and partial preservation / M.D. Craggs -- Cardiovascular dysfunction. The clinical problems in cardiovascular control following spinal cord injury: an overview / A. Krassioukov and V.E. Claydon. Orthostatic hypotension and paroxysmal hypertension in humans with high spinal cord injury / C.J. Mathias. Autonomic dysreflexia after spinal cord injury: central mechanisms and strategies for prevention / L.C. Weaver [and others] Segmental organization of spinal reflexes mediating autonomic dysreflexia after spinal cord injury / A.G. Rabchevsky. Spinal cord injury alters cardiac electrophysiology and increases the susceptibility to ventricular arrhythmias / H.L. Collins, D.W. Rodenbaugh, and S.E. DiCarlo. Adaptations of peripheral vasoconstrictor pathways after spinal cord injury / E.M. McLachlan and J.A. Brock. Genetic approaches to autonomic dysreflexia / A. Brown and J.E. Jacob -- Bowel dysfunction. Gastrointestinal symptoms related to autonomic dysfunction following spinal cord injury / E.A.L. Chung and A.V. Emmanuel. Colorectal motility and defecation after spinal cord injury in humans / A.C. Lynch and F.A. Frizelle. Mechanisms controlling normal defecation and the potential effects of spinal cord injury / A.F. Brading and T. Ramalingam. Alterations in eliminative and sexual reflexes after spinal cord injury: defecatory function and development of spasticity in pelvic floor musculature / Y.S. Nout [and others] Upper and lower gastrointestinal motor and sensory dysfunction after human spinal cord injury / P. Enck [and others] -- Sexual dysfunction. Problems of sexual function after spinal cord injury / S.L. Elliott. Ascending spinal pathways from sexual organs: effects of chronic spinal lesions / C.H. Hubscher. Descending pathways modulating the spinal circuitry for ejaculation: effects of chronic spinal cord injury / R.D. Johnson. Male fertility and sexual function after spinal cord injury / D.J. Brown, S.T. Hill, and H.W.G. Baker. Female sexual function after spinal cord injury / M.S. Sipski and A. Arenas.

Print version record.

Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions. The book begins with a description of the time course of autonomic dysfunctions and their ramifications from the first hours after a spinal cord injury to the more stable chronic states. The next section contains three chapters that address anatomical findings that may provide some of the foundation for autonomic dysfunctions in many of the systems. The system-specific chapters then follow in four sections. Each section begins with a chapter or two defining the clinical problems experienced by people with cord injury. The following chapters present research, basic and clinical, that address the autonomic dysfunctions.

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