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Bioinformatics : a Swiss perspective / editors, Ron D. Appel, Ernest Feytmans.

Contributor(s): Appel, Ron D | Feytmans, ErnestMaterial type: TextTextPublication details: New Jersey : World Scientific, ©2009. Description: 1 online resource (xx, 443 pages) : illustrations (some color)Content type: text Media type: computer Carrier type: online resourceISBN: 9789812838780; 9812838783; 1282442791; 9781282442795; 9789812838773; 9812838775Subject(s): Bioinformatics | NATURE -- Reference | SCIENCE -- Life Sciences -- General | SCIENCE -- Life Sciences -- Biology | Bioinformatics | Biology | Health & Biological Sciences | Biology - General | Computational Biology | Biology | Biological Science Disciplines | Natural Science Disciplines | Disciplines and OccupationsGenre/Form: Electronic books. | Electronic books. Additional physical formats: Print version:: Bioinformatics.DDC classification: 570.285 LOC classification: QH324.2 | .B54714 2009ebOnline resources: Click here to access online
Contents:
Methods for Discovery and Characterization of DNA Sequence Motifs / Philipp Bucher -- Comparative Genome Analysis / Robert M. Waterhouse [and others] -- From Modules to Models: Advanced Analysis Methods for Large-Scale Data / Sven Bergmann -- Integrated Analysis of Gene Expression Profiling Studies: Examples in Breast Cancer / Pratyaksha Wirapati [and others] -- Computational Biology of Small Regulatory RNAs / Mihaela Zavolan and Lukasz Jaskiewicz -- UniProtKB/Swiss-Prot Manual and Automated Annotation of Complete Proteomes: The Dictyostelium discoideum Case Study / Amos Bairoch and Lydie Lane -- Analytical Bioinformatics for Proteomics / Patricia M. Palagi, Frédérique Lisacek -- Protein-Protein Interaction Networks: Assembly and Analysis / Christian von Mering -- Protein Structure Modeling and Docking at the Swiss Institute of Bioinformatics / Torsten Schwede and Manuel C. Peitsch -- Molecular Modeling of Proteins: From Simulations to Drug Design Applications / Vincente Zoete [and others] -- An Introduction to Phylogenetics and Its Molecular Aspects / Gabriel J. Bittar and Bernhard Pascal Sonderegger -- Phylogenetic Tree Building Methods / Manuel Gil and Gaston H. Gonnet -- Bioinformatics for Evolutionary Developmental Biology / Marc Robinson-Rechavi -- Spatiotemporal Modeling and Simulation in Biology / Ivo F. Sbalzarini.
Summary: Biological research and recent technological advances have resulted in an enormous increase in research data that require large storage capacities, powerful computing resources, and accurate data analysis algorithms. Bioinformatics is the field that provides these resources to life science researchers. The Swiss Institute of Bioinformatics (SIB), which has celebrated its 10th anniversary in 2008, is an institution of national importance, recognized worldwide for its state-of-the-art work. Organized as a federation of bioinformatics research groups from Swiss universities and research institutes, the SIB provides services to the life science community that are highly appreciated worldwide, and coordinates research and education in bioinformatics nationwide. The SIB plays a central role in life science research both in Switzerland and abroad by developing extensive and high-quality bioinformatics resources that are essential for all life scientists. Knowledge developed by SIB members in areas such as genomics, proteomics, and systems biology is directly transformed by academia and industry into innovative solutions to improve global health. Such an astounding concentration of talent in a given field is unusual and unique in Switzerland. This book provides an insight into some of the key areas of activity in bioinformatics in Switzerland. With contributions from SIB members, it covers both research work and major infrastructure efforts in genome and gene expression analysis, investigations on proteins and proteomes, evolutionary bioinformatics, and modeling of biological systems.
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Includes bibliographical references and index.

Methods for Discovery and Characterization of DNA Sequence Motifs / Philipp Bucher -- Comparative Genome Analysis / Robert M. Waterhouse [and others] -- From Modules to Models: Advanced Analysis Methods for Large-Scale Data / Sven Bergmann -- Integrated Analysis of Gene Expression Profiling Studies: Examples in Breast Cancer / Pratyaksha Wirapati [and others] -- Computational Biology of Small Regulatory RNAs / Mihaela Zavolan and Lukasz Jaskiewicz -- UniProtKB/Swiss-Prot Manual and Automated Annotation of Complete Proteomes: The Dictyostelium discoideum Case Study / Amos Bairoch and Lydie Lane -- Analytical Bioinformatics for Proteomics / Patricia M. Palagi, Frédérique Lisacek -- Protein-Protein Interaction Networks: Assembly and Analysis / Christian von Mering -- Protein Structure Modeling and Docking at the Swiss Institute of Bioinformatics / Torsten Schwede and Manuel C. Peitsch -- Molecular Modeling of Proteins: From Simulations to Drug Design Applications / Vincente Zoete [and others] -- An Introduction to Phylogenetics and Its Molecular Aspects / Gabriel J. Bittar and Bernhard Pascal Sonderegger -- Phylogenetic Tree Building Methods / Manuel Gil and Gaston H. Gonnet -- Bioinformatics for Evolutionary Developmental Biology / Marc Robinson-Rechavi -- Spatiotemporal Modeling and Simulation in Biology / Ivo F. Sbalzarini.

Print version record.

Biological research and recent technological advances have resulted in an enormous increase in research data that require large storage capacities, powerful computing resources, and accurate data analysis algorithms. Bioinformatics is the field that provides these resources to life science researchers. The Swiss Institute of Bioinformatics (SIB), which has celebrated its 10th anniversary in 2008, is an institution of national importance, recognized worldwide for its state-of-the-art work. Organized as a federation of bioinformatics research groups from Swiss universities and research institutes, the SIB provides services to the life science community that are highly appreciated worldwide, and coordinates research and education in bioinformatics nationwide. The SIB plays a central role in life science research both in Switzerland and abroad by developing extensive and high-quality bioinformatics resources that are essential for all life scientists. Knowledge developed by SIB members in areas such as genomics, proteomics, and systems biology is directly transformed by academia and industry into innovative solutions to improve global health. Such an astounding concentration of talent in a given field is unusual and unique in Switzerland. This book provides an insight into some of the key areas of activity in bioinformatics in Switzerland. With contributions from SIB members, it covers both research work and major infrastructure efforts in genome and gene expression analysis, investigations on proteins and proteomes, evolutionary bioinformatics, and modeling of biological systems.

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