TY - BOOK AU - O'Hagan,Derek T. TI - Vaccine adjuvants: preparation methods and research protocols T2 - Methods in molecular medicine SN - 9781592590834 AV - QR187.3 .V33 2000 U1 - 615/.372 21 PY - 2000/// CY - Totowa, N.J. PB - Humana Press KW - Immunological adjuvants KW - Vaccines KW - Adjuvants, Immunologic KW - Immunologic Factors KW - Biological Products KW - Complex Mixtures KW - Physiological Effects of Drugs KW - Chemicals and Drugs KW - Pharmacologic Actions KW - Chemical Actions and Uses KW - MEDICAL KW - Pharmacology KW - bisacsh KW - fast KW - Wetenschappelijke technieken KW - gtt KW - Electronic books N1 - Source of title; title from title screen; Includes bibliographical references and index; An overview of adjuvant use -- Harmful and beneficial activities of immunological adjuvants -- Freund's adjuvants -- Aluminum compounds as vaccine adjuvants -- Poly(lactice-coglycolide) microparticles as vaccine adjuvants -- Poly(methyl methacrylate) nanoparticles as vaccine adjuvants -- Aqueous formulation of adjuvant-active nonionic block copolymers -- Liposomes as immunological adjuvants and vaccine carriers -- Immunopotentiating reconstituted indluezna virosomes (IRIVs) -- Cochleates for induction of mucosal and systemic immune responses -- Virus-like particles as vaccine adjuvants -- The adjuvant MF59: a 10 year perspective -- Preparation of the syntex adjuvant formulation (SAF, SAF-m, SAF-1) -- The ISCOM technology -- QS-21 adjuvant -- MPL Immunostimulant: adjuvant formulations -- Cytokines as vaccine adjuvants: the use of interleukin-2 -- DNA as an adjuvant -- Transcutaneous immunizaation -- Mutant heat-lbile enterotoxins as adjuvants for CTL induction; Electronic reproduction; [Place of publication not identified]; HathiTrust Digital Library; 2010 N2 - Annotation; Derek T. O'Hagan and a team of expert vaccinologists and pharmacologists thoroughly describe the preparation, characterization, and evaluation of a wide range of alternative vaccine adjuvants for use in preclinical studies. Each chapter carefully reviews a single adjuvant, and suggests why a specific adjuvant might be preferred for a given antigen, depending on what type of immune response is desired. Alternate adjuvant choices are also presented so that researchers can choose those most efficacious for their specific purpose. Comprehensive and highly practical, Vaccine Adjuvants: Preparation Methods and Research Protocols provides an effective guide to making and using vaccine adjuvants. By closely following directions from the book, today's researchers will be able optimally to induce specific immune responses against different types of antigens and to selectively manipulate the immune response in a favorable way UR - https://link-springer-com.libraryproxy.ist.ac.at/10.1385/1592590837 ER -